dc.contributor.author |
Ke, Nengwen |
|
dc.contributor.author |
Jia, Dan |
|
dc.contributor.author |
Huang, Wei |
|
dc.contributor.author |
Nunes, Quentin M |
|
dc.contributor.author |
Windsor, John A |
|
dc.contributor.author |
Liu, Xubao |
|
dc.contributor.author |
Sutton, Robert |
|
dc.coverage.spatial |
United States |
|
dc.date.accessioned |
2023-02-09T03:19:27Z |
|
dc.date.available |
2023-02-09T03:19:27Z |
|
dc.date.issued |
2018-05 |
|
dc.identifier.citation |
(2018). Medicine, 97(19), e0651-. |
|
dc.identifier.issn |
0304-5412 |
|
dc.identifier.uri |
https://hdl.handle.net/2292/62730 |
|
dc.description.abstract |
The timing of surgery for painful chronic pancreatitis (CP) may affect outcomes.Clinical course, Izbicki pain scores, and pancreatic function were retrospectively compared and analyzed between patients undergoing either early or late surgery (< 3 or ≥ 3 years from diagnosis) for painful CP in a single center from 2007 to 2012.The early surgery group (n = 98) more frequently than the late group (n = 199) had abdominal pain with jaundice (22.4% vs 9.5%, P = .002) and pancreatic mass +/- ductal dilatation (47% vs 27%, P < .001), but less frequently abdominal pain alone (73.5% vs 85.9%, P = .009), ductal dilatation alone (31% vs 71%, P < .001), parenchymal calcification (91.8% vs 100%, P < .001) or exocrine insufficiency (60% vs 72%, P = .034); there were no other significant differences. The early group had longer hospital stay (14.4 vs 12.2 days, P = .009), but no difference in complications. Significantly greater pain relief followed early surgery (complete 69% vs 47%, partial 22% vs 37%, none 8% vs 16%, P = .01) with lower rates of exocrine (60% vs 80%, P = .005) and endocrine insufficiency (36% vs 53%, P = .033).Our data indicate that early surgery results in higher rates of pain relief and pancreatic sufficiency than late surgery for chronic pancreatitis patients. Frey and Berne procedures showed better results than other surgical procedures. |
|
dc.format.medium |
Print |
|
dc.language |
eng |
|
dc.publisher |
Wolters Kluwer |
|
dc.relation.ispartofseries |
Medicine |
|
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
|
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
|
dc.rights.uri |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
|
dc.subject |
Pancreas |
|
dc.subject |
Pancreatic Ducts |
|
dc.subject |
Humans |
|
dc.subject |
Calcinosis |
|
dc.subject |
Dilatation, Pathologic |
|
dc.subject |
Jaundice |
|
dc.subject |
Intraoperative Complications |
|
dc.subject |
Postoperative Complications |
|
dc.subject |
Abdominal Pain |
|
dc.subject |
Digestive System Surgical Procedures |
|
dc.subject |
Time Factors |
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dc.subject |
Middle Aged |
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dc.subject |
Female |
|
dc.subject |
Male |
|
dc.subject |
Pancreatitis, Chronic |
|
dc.subject |
Clinical Research |
|
dc.subject |
Pain Research |
|
dc.subject |
Chronic Pain |
|
dc.subject |
Pancreatic Cancer |
|
dc.subject |
Cancer |
|
dc.subject |
Digestive Diseases |
|
dc.subject |
Rare Diseases |
|
dc.subject |
6 Evaluation of treatments and therapeutic interventions |
|
dc.subject |
6.4 Surgery |
|
dc.subject |
Oral and gastrointestinal |
|
dc.subject |
Science & Technology |
|
dc.subject |
Life Sciences & Biomedicine |
|
dc.subject |
Medicine, General & Internal |
|
dc.subject |
General & Internal Medicine |
|
dc.subject |
chronic pancreatitis |
|
dc.subject |
endocrine pancreatic insufficiency |
|
dc.subject |
exocrine pancreatic insufficiency |
|
dc.subject |
pain relief |
|
dc.subject |
surgery |
|
dc.subject |
SURGICAL DRAINAGE |
|
dc.subject |
ANTIOXIDANT THERAPY |
|
dc.subject |
TREATMENT OPTIONS |
|
dc.subject |
FOLLOW-UP |
|
dc.subject |
QUALITY |
|
dc.subject |
PANCREATICODUODENECTOMY |
|
dc.subject |
METAANALYSIS |
|
dc.subject |
MANAGEMENT |
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dc.subject |
FREY |
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dc.subject |
1103 Clinical Sciences |
|
dc.subject |
Clinical |
|
dc.subject |
Clinical Medicine and Science |
|
dc.subject |
Pain Conditions - Chronic |
|
dc.title |
Earlier surgery improves outcomes from painful chronic pancreatitis. |
|
dc.type |
Journal Article |
|
dc.identifier.doi |
10.1097/md.0000000000010651 |
|
pubs.issue |
19 |
|
pubs.begin-page |
e0651 |
|
pubs.volume |
97 |
|
dc.date.updated |
2023-01-06T22:38:48Z |
|
dc.rights.holder |
Copyright: the authors |
en |
dc.identifier.pmid |
29742705 (pubmed) |
|
pubs.author-url |
https://www.ncbi.nlm.nih.gov/pubmed/29742705 |
|
pubs.publication-status |
Published |
|
dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
en |
pubs.subtype |
research-article |
|
pubs.subtype |
Journal Article |
|
pubs.subtype |
Observational Study |
|
pubs.elements-id |
740023 |
|
pubs.org-id |
Medical and Health Sciences |
|
pubs.org-id |
Science |
|
pubs.org-id |
Science Research |
|
pubs.org-id |
School of Medicine |
|
pubs.org-id |
Surgery Department |
|
pubs.org-id |
Maurice Wilkins Centre (2010-2014) |
|
dc.identifier.eissn |
1536-5964 |
|
dc.identifier.pii |
00005792-201805110-00024 |
|
pubs.number |
ARTN e0651 |
|
pubs.record-created-at-source-date |
2023-01-07 |
|
pubs.online-publication-date |
2018-05-11 |
|