dc.contributor.author |
Merry, AF |
|
dc.contributor.author |
van Waart, H |
|
dc.contributor.author |
Allen, SJ |
|
dc.contributor.author |
Baker, PA |
|
dc.contributor.author |
Cumin, D |
|
dc.contributor.author |
Frampton, CMA |
|
dc.contributor.author |
Gargiulo, DA |
|
dc.contributor.author |
Hannam, JA |
|
dc.contributor.author |
Keogh, GF |
|
dc.contributor.author |
Moore, MR |
|
dc.contributor.author |
Payton, M |
|
dc.contributor.author |
Mitchell, SJ |
|
dc.coverage.spatial |
England |
|
dc.date.accessioned |
2023-02-10T01:59:36Z |
|
dc.date.available |
2023-02-10T01:59:36Z |
|
dc.date.issued |
2022-12 |
|
dc.identifier.citation |
(2022). Anaesthesia, 77(12), 1346-1355. |
|
dc.identifier.issn |
0003-2409 |
|
dc.identifier.uri |
https://hdl.handle.net/2292/62756 |
|
dc.description.abstract |
The Difficult Airway Society recommends that all patients should be pre-oxygenated before the induction of general anaesthesia, but this may not always be easy or comfortable and anaesthesia may often be induced without full pre-oxygenation. We tested the hypothesis that high-flow nasal oxygen cannulae would be easier and more comfortable than facemasks for pre-oxygenation. We randomly allocated 199 patients undergoing elective surgery aged ≥ 10 years to pre-oxygenation using either high-flow nasal oxygen or facemask. Ease and comfort were assessed by anaesthetists and patients on 10-cm visual analogue scale and six-point smiley face scale, respectively. Secondary endpoints included end-tidal oxygen fraction after securing a definitive airway and time to secure an airway. A mean difference (95%CI) between groups in ratings of -0.76 (-1.25 to -0.27) cm for ease of use (p = 0.003) and -0.45 (-0.75 to -0.13) points for comfort (p = 0.006), both favoured high-flow nasal oxygen. A mean difference (95%CI) between groups in end-tidal oxygen fraction of 3.89% (2.41-5.37%) after securing a definitive airway also favoured high-flow nasal oxygen (p < 0.001). There was no significant difference between groups in the number of patients with hypoxaemia (S<sub>p</sub> O<sub>2</sub> < 90%) or severe hypoxaemia (S<sub>p</sub> O<sub>2</sub> < 85%) lasting ≥ 1 min or ≥ 2 min; in the proportion of patients with an end-tidal oxygen fraction < 87% in the first 5 min after tracheal intubation (52.2% vs. 58.9% in facemask and high-flow nasal oxygen groups, respectively; p = 0.31); or in time taken to secure an airway (11.6 vs. 12.2 min in facemask and high-flow nasal oxygen groups, respectively; p = 0.65). In conclusion, we found pre-oxygenation with high-flow nasal oxygen to be easier for anaesthetists and more comfortable for patients than pre-oxygenation with a facemask, with no clinically relevant differences in end-tidal oxygen fraction after securing a definitive airway or time to secure an airway. The differences in ease and comfort were modest. |
|
dc.format.medium |
Print-Electronic |
|
dc.language |
eng |
|
dc.publisher |
Wiley |
|
dc.relation.ispartofseries |
Anaesthesia |
|
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
|
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
|
dc.rights.uri |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
|
dc.subject |
Humans |
|
dc.subject |
Oxygen |
|
dc.subject |
Oxygen Inhalation Therapy |
|
dc.subject |
Administration, Intranasal |
|
dc.subject |
Masks |
|
dc.subject |
Hypoxia |
|
dc.subject |
Cannula |
|
dc.subject |
airway management |
|
dc.subject |
high-flow nasal oxygenation |
|
dc.subject |
pre-oxygenation |
|
dc.subject |
transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) |
|
dc.subject |
Lung |
|
dc.subject |
Respiratory |
|
dc.subject |
1103 Clinical Sciences |
|
dc.subject |
1109 Neurosciences |
|
dc.title |
Ease and comfort of pre-oxygenation with high-flow nasal oxygen cannulae vs. facemask: a randomised controlled trial. |
|
dc.type |
Journal Article |
|
dc.identifier.doi |
10.1111/anae.15853 |
|
pubs.issue |
12 |
|
pubs.begin-page |
1346 |
|
pubs.volume |
77 |
|
dc.date.updated |
2023-01-26T00:21:08Z |
|
dc.rights.holder |
Copyright: The authors |
en |
dc.identifier.pmid |
36110039 (pubmed) |
|
pubs.author-url |
https://www.ncbi.nlm.nih.gov/pubmed/36110039 |
|
pubs.end-page |
1355 |
|
pubs.publication-status |
Published |
|
dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
en |
pubs.subtype |
research-article |
|
pubs.subtype |
Randomized Controlled Trial |
|
pubs.subtype |
Journal Article |
|
pubs.elements-id |
919979 |
|
pubs.org-id |
Medical and Health Sciences |
|
pubs.org-id |
Medical Sciences |
|
pubs.org-id |
Pharmacology |
|
pubs.org-id |
Pharmacy |
|
pubs.org-id |
School of Medicine |
|
pubs.org-id |
Anaesthesiology |
|
dc.identifier.eissn |
1365-2044 |
|
pubs.record-created-at-source-date |
2023-01-26 |
|
pubs.online-publication-date |
2022-09-15 |
|