dc.contributor.author |
Gebremariam, Girma Tekle |
|
dc.contributor.author |
Biratu, Selam |
|
dc.contributor.author |
Alemayehu, Metasebia |
|
dc.contributor.author |
Welie, Abraham Gebregziabiher |
|
dc.contributor.author |
Beyene, Kebede |
|
dc.contributor.author |
Sander, Beate |
|
dc.contributor.author |
Gebretekle, Gebremedhin Beedemariam |
|
dc.contributor.editor |
Suppiah, Vijayaprakash |
|
dc.coverage.spatial |
United States |
|
dc.date.accessioned |
2023-03-09T22:24:18Z |
|
dc.date.available |
2023-03-09T22:24:18Z |
|
dc.date.issued |
2022-01 |
|
dc.identifier.citation |
(2022). PLoS One, 17(2), e0264199-. |
|
dc.identifier.issn |
1932-6203 |
|
dc.identifier.uri |
https://hdl.handle.net/2292/63267 |
|
dc.description.abstract |
<h4>Background</h4>Type 2 diabetes mellitus (T2DM) and its treatment impact patients' physical health as well as emotional and social wellbeing. This study aimed to assess health-related quality of life (HRQoL) and associated factors among patients with T2DM at a tertiary care hospital in Ethiopia.<h4>Methods</h4>A face-to-face cross-sectional survey was conducted among patients with T2DM at Tikur Anbessa Specialized Hospital in Addis Ababa, Ethiopia. We collected data using a validated Amharic version of the 5-level EuroQoL-5 dimensions (EQ-5D-5L) questionnaire. Descriptive statistics were used to present patient characteristics. Kruskal-Wallis and Mann-Whitney U tests were performed to explore differences in the median scores of EQ-5D-5L utility and visual analog scale (EQ-VAS). Multivariable Tobit regression models were used to identify predictors of HRQoL. Utility scores were calculated using disutility weights of the Ethiopian general population. Statistical significance was determined at p < 0.05.<h4>Results</h4>A total of 360 patients with T2DM participated. Mean (SD) age was 64.43(10.61) years. Reported health problems were mostly in the pain/discomfort (67.3%) dimension followed by mobility (60.5%), whereas the usual activities domain (34.1%) was the least health problem being reported. The median (IQR) EQ-5D-5L utility and EQ-VAS scores were 0.95 (0.88-0.96) and 80 (75.0-85.0), respectively. In multivariable Tobit regression models older age, having poor glycemic control, longer duration of diabetes, insulin usage, obesity, and having diabetes-related complications were significant negative predictors of HRQoL.<h4>Conclusions</h4>Overall, patients with T2DM had lower HRQoL than the general population, which was attributed to being older age, longer duration of diabetes, insulin use, obesity, inadequate glycemic control, and diabetes-related complications. The utility index we generated can be used in future economic evaluations to inform decisions about alternative interventions and resource allocation. |
|
dc.format.medium |
Electronic-eCollection |
|
dc.language |
eng |
|
dc.publisher |
Public Library of Science (PLoS) |
|
dc.relation.ispartofseries |
PloS one |
|
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
|
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
|
dc.rights.uri |
https://creativecommons.org/licenses/by/4.0/ |
|
dc.subject |
Humans |
|
dc.subject |
Diabetes Mellitus, Type 2 |
|
dc.subject |
Quality of Life |
|
dc.subject |
Aged |
|
dc.subject |
Middle Aged |
|
dc.subject |
Ethiopia |
|
dc.subject |
Female |
|
dc.subject |
Male |
|
dc.subject |
Tertiary Care Centers |
|
dc.subject |
Diabetes |
|
dc.subject |
Clinical Research |
|
dc.subject |
Aging |
|
dc.subject |
Obesity |
|
dc.subject |
7.1 Individual care needs |
|
dc.subject |
7 Management of diseases and conditions |
|
dc.subject |
Metabolic and endocrine |
|
dc.subject |
3 Good Health and Well Being |
|
dc.title |
Health-related quality of life of patients with type 2 diabetes mellitus at a tertiary care hospital in Ethiopia. |
|
dc.type |
Journal Article |
|
dc.identifier.doi |
10.1371/journal.pone.0264199 |
|
pubs.issue |
2 |
|
pubs.begin-page |
e0264199 |
|
pubs.volume |
17 |
|
dc.date.updated |
2023-02-05T03:56:32Z |
|
dc.rights.holder |
Copyright: The authors |
en |
dc.identifier.pmid |
35180266 (pubmed) |
|
pubs.author-url |
https://www.ncbi.nlm.nih.gov/pubmed/35180266 |
|
pubs.publication-status |
Published |
|
dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
en |
pubs.subtype |
Research Support, Non-U.S. Gov't |
|
pubs.subtype |
research-article |
|
pubs.subtype |
Journal Article |
|
pubs.elements-id |
888313 |
|
dc.identifier.eissn |
1932-6203 |
|
dc.identifier.pii |
PONE-D-21-20037 |
|
pubs.record-created-at-source-date |
2023-02-05 |
|
pubs.online-publication-date |
2022-02-18 |
|