dc.contributor.author |
Lessa, Roberta Cardim |
|
dc.contributor.author |
Alves, Fabio de Abreu |
|
dc.contributor.author |
Fortunati, Erika |
|
dc.contributor.author |
Lu, Jun |
|
dc.coverage.spatial |
Switzerland |
|
dc.date.accessioned |
2023-04-17T02:01:30Z |
|
dc.date.available |
2023-04-17T02:01:30Z |
|
dc.date.issued |
2021-10 |
|
dc.identifier.citation |
(2021). Biomedicines, 9(11), 1531-. |
|
dc.identifier.issn |
2227-9059 |
|
dc.identifier.uri |
https://hdl.handle.net/2292/63624 |
|
dc.description.abstract |
Oral mucositis (OM) is a painful condition caused by chemotherapeutic or radiotherapeutic cancer treatments, occurring in patients with different tumour characteristics and locations. OM greatly impacts a patient's quality of life and cancer recovery. Current OM management strategies are not providing sufficient prevention and treatment; new approaches to injury management are needed. Studies on the benefit of omega-3 free fatty acids (FFA) in human health have increased significantly in recent years. FFA properties have been studied extensively, including their potential therapeutic use in inflammatory conditions. However, omega-3 FFA's use as a supplementary treatment for OM has not been clinically tested. Preliminary evidence suggests that utilising FFA to manage OM could be a useful strategy for lesion management, assisting with healthy oral mucosa recovery. This review will describe the incidence, risk factors, biology of OM and the current treatment strategies, leading to a discussion of the utility of omega-3 FFA as a novel therapeutic agent for OM. |
|
dc.format.medium |
Electronic |
|
dc.language |
eng |
|
dc.publisher |
MDPI |
|
dc.relation.ispartofseries |
Biomedicines |
|
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
|
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
|
dc.rights.uri |
https://creativecommons.org/licenses/by/4.0/ |
|
dc.subject |
cancer |
|
dc.subject |
cytokines |
|
dc.subject |
inflammation |
|
dc.subject |
interleukins |
|
dc.subject |
leukotrienes |
|
dc.subject |
omega-3 fatty acids |
|
dc.subject |
omega-6 fatty acids |
|
dc.subject |
oral mucositis |
|
dc.subject |
polyunsaturated fatty acids |
|
dc.subject |
prostaglandins |
|
dc.subject |
Nutrition |
|
dc.subject |
Rare Diseases |
|
dc.subject |
Complementary and Integrative Health |
|
dc.subject |
Dental/Oral and Craniofacial Disease |
|
dc.subject |
Prevention |
|
dc.title |
Oral Mucositis in Cancer and Potential Use of Omega-3 Free Fatty Acids in Its Management: A Review. |
|
dc.type |
Journal Article |
|
dc.identifier.doi |
10.3390/biomedicines9111531 |
|
pubs.issue |
11 |
|
pubs.begin-page |
1531 |
|
pubs.volume |
9 |
|
dc.date.updated |
2023-03-18T09:34:02Z |
|
dc.rights.holder |
Copyright: The authors |
en |
dc.identifier.pmid |
34829760 (pubmed) |
|
pubs.author-url |
https://www.ncbi.nlm.nih.gov/pubmed/34829760 |
|
pubs.publication-status |
Published |
|
dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
en |
pubs.subtype |
review-article |
|
pubs.subtype |
Review |
|
pubs.subtype |
Journal Article |
|
pubs.elements-id |
945832 |
|
pubs.org-id |
Bioengineering Institute |
|
dc.identifier.eissn |
2227-9059 |
|
dc.identifier.pii |
biomedicines9111531 |
|
pubs.record-created-at-source-date |
2023-03-18 |
|
pubs.online-publication-date |
2021-10-25 |
|