Optical System for an Inexpensive Disease Diagnosis

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dc.contributor.advisor Taberner, A en
dc.contributor.author Lopez Muedano, Carlos en
dc.date.accessioned 2011-02-22T00:59:03Z en
dc.date.issued 2011 en
dc.identifier.uri http://hdl.handle.net/2292/6399 en
dc.description Full text is available to authenticated members of The University of Auckland only. en
dc.description.abstract The use of antibody-based diagnostic testing has increased significantly over the past decade. Most rapid point-of-care tests are based on manual assays using immunochromatographic strips (also known as "strip tests") which provide a qualitative positive or negative test outcome. Alternatively, quantitative diagnostic tests require the use of dedicated and expensive instruments making them ill-suited for small to mid-size clinical testing laboratories. An optical device was developed to read immunodiagnostic test results using commercially available components. This low cost portable instrument consists of a webcam, a white LED, two lasers and a long pass filter housed in an acrylic body. This device was used to read results from an array of antibodies conjugated with either an enzymatic or fluorescent tag resulting in a coloured or fluorescent readout. The presence of analyte was recorded as a change of red, green and blue (%RGB) colour, both as a time-course and end-point assay. A prototype of a low cost, portable analysis system has been developed en
dc.publisher ResearchSpace@Auckland en
dc.relation.ispartof Masters Thesis - University of Auckland en
dc.relation.isreferencedby UoA99218286714002091 en
dc.rights Restricted Item. Available to authenticated members of The University of Auckland. en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.title Optical System for an Inexpensive Disease Diagnosis en
dc.type Thesis en
thesis.degree.discipline Bioengineering en
thesis.degree.grantor The University of Auckland en
thesis.degree.level Masters en
dc.rights.holder Copyright: the author en
pubs.elements-id 206423 en
pubs.record-created-at-source-date 2011-02-22 en

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