dc.contributor.author |
Hill, Nicole S |
|
dc.contributor.author |
Cormack, Barbara E |
|
dc.contributor.author |
Little, Bridget S |
|
dc.contributor.author |
Bloomfield, Frank H |
|
dc.coverage.spatial |
United States |
|
dc.date.accessioned |
2024-04-07T22:42:05Z |
|
dc.date.available |
2024-04-07T22:42:05Z |
|
dc.date.issued |
2020-09 |
|
dc.identifier.citation |
(2020). Journal of Parenteral and Enteral Nutrition, 44(7), 1318-1327. |
|
dc.identifier.issn |
0148-6071 |
|
dc.identifier.uri |
https://hdl.handle.net/2292/68045 |
|
dc.description.abstract |
<h4>Background</h4>Very low-birth-weight (VLBW; birth weight < 1500 g) infants are often dependent on intravenous nutrition after birth. Conventional soy-based intravenous lipid emulsions (Soy LE) are associated with inflammatory and metabolic complications that may be harmful to preterm infants. Evidence to support any clinical benefit associated with newer multicomponent emulsions (Mixed LE), remains inconsistent and unsubstantiated in appropriate studies. This retrospective study aimed to determine whether growth and clinical outcomes differed between VLBW infants given Mixed LE vs Soy LE at Auckland City Hospital.<h4>Methods</h4>Data were collected on nutrition, growth, and neonatal morbidities for the first 4 weeks after birth. Outcomes were compared between 2 lipid cohorts, Soy LE (February 2013 - August 2014) and Mixed LE (August 2014 - December 2015), using univariate and multivariate analysis.<h4>Results</h4>207 infants (Soy LE, 105 vs Mixed LE, 102) were included in the study. Significantly fewer infants in the Mixed LE cohort developed any stage retinopathy of prematurity (Soy LE 59% vs Mixed LE 39%, P = .005) or intraventricular hemorrhage (Soy LE 27% vs Mixed LE 15%, P = .03) during their admission. Mixed LE was also associated with significantly lower mean (P = .01), minimum (P = .03), and maximum (P = .04) total bilirubin concentrations across the first 4 weeks after birth. There was no difference in growth velocity or weight, length, and head circumference z-score change.<h4>Conclusion</h4>SMOFlipid may represent a favorable alternative to conventional lipid emulsions in neonatal parenteral nutrition regimens; however, long-term effects should be further evaluated. |
|
dc.format.medium |
Print-Electronic |
|
dc.language |
eng |
|
dc.publisher |
Wiley |
|
dc.relation.ispartofseries |
JPEN. Journal of parenteral and enteral nutrition |
|
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
|
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
|
dc.subject |
Humans |
|
dc.subject |
Soybean Oil |
|
dc.subject |
Fat Emulsions, Intravenous |
|
dc.subject |
Triglycerides |
|
dc.subject |
Fish Oils |
|
dc.subject |
Parenteral Nutrition |
|
dc.subject |
Retrospective Studies |
|
dc.subject |
Infant |
|
dc.subject |
Infant, Newborn |
|
dc.subject |
Infant, Very Low Birth Weight |
|
dc.subject |
Infant, Premature |
|
dc.subject |
Olive Oil |
|
dc.subject |
life cycle |
|
dc.subject |
lipids |
|
dc.subject |
neonates |
|
dc.subject |
nutrition |
|
dc.subject |
preterm |
|
dc.subject |
3213 Paediatrics |
|
dc.subject |
32 Biomedical and Clinical Sciences |
|
dc.subject |
Infant Mortality |
|
dc.subject |
Perinatal Period - Conditions Originating in Perinatal Period |
|
dc.subject |
Preterm, Low Birth Weight and Health of the Newborn |
|
dc.subject |
Pediatric |
|
dc.subject |
Clinical Research |
|
dc.subject |
Reproductive health and childbirth |
|
dc.subject |
3 Good Health and Well Being |
|
dc.subject |
Science & Technology |
|
dc.subject |
Life Sciences & Biomedicine |
|
dc.subject |
Nutrition & Dietetics |
|
dc.subject |
NUTRITION-ASSOCIATED CHOLESTASIS |
|
dc.subject |
MEDIUM-CHAIN TRIGLYCERIDES |
|
dc.subject |
FISH-OIL |
|
dc.subject |
PARENTERAL-NUTRITION |
|
dc.subject |
FATTY-ACIDS |
|
dc.subject |
DOCOSAHEXAENOIC ACID |
|
dc.subject |
LIVER-DISEASE |
|
dc.subject |
DOUBLE-BLIND |
|
dc.subject |
PRETERM INFANTS |
|
dc.subject |
1114 Paediatrics and Reproductive Medicine |
|
dc.subject |
Clinical |
|
dc.subject |
Clinical Medicine and Science |
|
dc.subject |
Prevention |
|
dc.subject |
Oral and Gastrointestinal |
|
dc.subject |
11 Medical and Health Sciences |
|
dc.subject |
3202 Clinical sciences |
|
dc.subject |
3210 Nutrition and dietetics |
|
dc.title |
Growth and Clinical Outcome in Very Low-Birth-Weight Infants After the Introduction of a Multicomponent Intravenous Lipid Emulsion. |
|
dc.type |
Journal Article |
|
dc.identifier.doi |
10.1002/jpen.1750 |
|
pubs.issue |
7 |
|
pubs.begin-page |
1318 |
|
pubs.volume |
44 |
|
dc.date.updated |
2024-03-10T22:15:13Z |
|
dc.rights.holder |
Copyright: American Society for Parenteral and Enteral Nutrition |
en |
dc.identifier.pmid |
31989691 (pubmed) |
|
pubs.author-url |
https://www.ncbi.nlm.nih.gov/pubmed/31989691 |
|
pubs.end-page |
1327 |
|
pubs.publication-status |
Published |
|
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RetrictedAccess |
en |
pubs.subtype |
Journal Article |
|
pubs.elements-id |
870605 |
|
pubs.org-id |
Liggins Institute |
|
pubs.org-id |
University management |
|
pubs.org-id |
LiFePATH |
|
pubs.org-id |
Office of the Vice-Chancellor |
|
dc.identifier.eissn |
1941-2444 |
|
pubs.record-created-at-source-date |
2024-03-11 |
|
pubs.online-publication-date |
2020-01-28 |
|