How to diagnose dry anophthalmic socket syndrome (DASS) in the clinical routine

Abstract

The editorial "How to analyze conjunctival inflammation in dry anophthalmic socket syndrome (DASS)?" by our highly esteemed colleague and friend Frederic Mouriaux was of great interest to us. Fortunately, the knowledge regarding DASS is increasing and the pathophysiology of DASS is beginning to be understood. Conjunctival inflammation is one of the key factors in DASS, most likely even the cardinal factor and should therefore be targeted for successful treatment. However, Frederic Mouriaux leaves two unanswered questions in the diagnosis of DASS concerning conjunctival inflammation and the impact on therapeutic management: Do we need to measure the MMP-9 by immunoassay in all patients having anophthalmic sockets? And do we need to measure the TFO in all patients having anophthalmic sockets?