A Coupled soft tissue continuum-transient blood flow model to investigate the circulation in deep veins of the calf under compression

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dc.contributor.author Mithraratne, Premakumar en
dc.contributor.author Lavrijsen, T en
dc.contributor.author Hunter, Peter en
dc.contributor.editor Lim, CT en
dc.contributor.editor Goh, JCH en
dc.coverage.spatial Singapore en
dc.date.accessioned 2011-08-16T03:21:03Z en
dc.date.issued 2009 en
dc.identifier.citation 13th International Conference on Biomedical Engineering, Singapore, 03 Dec 2008 - 06 Dec 2008. Editors: Lim CT, Goh JCH. IFMBE Proceedings. 23: 1878-1882. 2009 en
dc.identifier.isbn 978-3-540-92840-9 en
dc.identifier.issn 1680-0737 en
dc.identifier.uri http://hdl.handle.net/2292/7338 en
dc.description.abstract A coupled computational model of a 3D soft tissue continuum and a one-dimensional transient blood flow network is presented in this paper. The primary aim of the model is to investigate the reduction in vessel cross section area and resulting vessel wall shear stresses (WSS) in response to the compression applied on the calf. Application of external compression on the lower leg is a commonly used prophylaxis against thrombus formation in deep veins. The soft tissue continuum model is a tri-cubic Hermite finite element mesh representing all the muscles, skin and subcutaneous fat in the calf and treated as incompressible with homogeneous isotropic properties. The deformed state of the soft tissue due to the applied compression is obtained by solving large or nonlinear deformation mechanics equations using the Galerkin finite element method. The geometry of the main deep vein network is represented by a 1D Hermite cubic finite element mesh. The flow computational model consists of 1D Navier-Stokes equations and a non-linear constitutive equation to describe vessel radius - transmural pressure relationship. Once compression is applied, the transmural pressure is computed as the difference between the fluid and soft tissue hydrostatic pressure. The latter arises due to the incompressibility of the soft tissue material. Transient flow governing equations are solved using the McCormack finite difference method. The geometry of both the soft tissue continuum and vein network is anatomicallybased and was developed using data derived from magnetic resonance images (MRI). Simulation results from the computational model show a reasonably good agreement with the results reported in the literature on the degree of deformation in vein cross-section area estimated using MRI. en
dc.description.uri http://www.springerlink.com/content/h6x656870p706767/?p=482cbc6e096d42dab2ca1eebb7500a5b&pi=0 en
dc.relation.ispartof 13th International Conference on Biomedical Engineering en
dc.relation.ispartofseries IFMBE Proceedings en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/1680-0737/ en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.subject Deep Veins en
dc.subject Blood flow mechanics en
dc.subject Soft tissue mechanics en
dc.subject SHEAR-STRESS en
dc.subject LOWER LEG en
dc.subject STOCKINGS en
dc.subject HEMODYNAMICS en
dc.subject DEFORMATION en
dc.subject PREVENTION en
dc.subject THROMBOSIS en
dc.subject POSITION en
dc.subject STASIS en
dc.title A Coupled soft tissue continuum-transient blood flow model to investigate the circulation in deep veins of the calf under compression en
dc.type Conference Item en
dc.identifier.doi 10.1007/978-3-540-92841-6_466 en
pubs.issue 1-3 en
pubs.begin-page 1878 en
pubs.volume 23 en
dc.rights.holder Copyright: 2008 ICBME en
pubs.end-page 1882 en
pubs.finish-date 2008-12-06 en
pubs.start-date 2008-12-03 en
dc.rights.accessrights http://purl.org/eprint/accessRights/RestrictedAccess en
pubs.subtype Proceedings en
pubs.elements-id 93233 en
pubs.org-id Bioengineering Institute en
pubs.org-id ABI Associates en
pubs.org-id Science en
pubs.org-id Science Research en
pubs.org-id Maurice Wilkins Centre (2010-2014) en
pubs.record-created-at-source-date 2010-09-01 en

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