Frequency response of implantable blood pressure telemetry systems

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dc.contributor.author McCormick, John en
dc.contributor.author Budgett, David en
dc.contributor.author Lim, Matthew en
dc.contributor.author Van Vliet, B en
dc.contributor.author Nielsen, Poul en
dc.contributor.author Hu, Aiguo en
dc.contributor.author Malpas, Simon en
dc.date.accessioned 2011-09-04T21:18:54Z en
dc.date.issued 2010-08 en
dc.identifier.citation Clin Exp Pharmacol Physiol 37(8):862-869 Aug 2010 en
dc.identifier.issn 0305-1870 en
dc.identifier.uri http://hdl.handle.net/2292/7598 en
dc.description.abstract 1. Measurement of blood pressure via telemetry in a variety of animal species has become an indispensable part of cardiovascular physiology, drug development and safety pharmacology. 2. These telemetry systems use fluid-filled catheters, which differ from commonly encountered indwelling catheters by virtue of their short length, high durometer, variable inner diameter and the use of a gel interface at the distal tip. 3. Despite the widespread use of blood pressure telemetry, there is little information describing the frequency response of these systems. The frequency response is of importance because it determines how well the waveform dynamics, such as pulse pressure, are captured. 4. For this reason, we measured the frequency responses of commonly used telemeters manufactured by Data Sciences International (St Paul, MN, USA; namely PA-C10, PA-C40 and PA-D70) and Telemetry Research (TR43P). The mean (± SEM) –3 dB frequencies measured for the PA-C10, PA-C40, PA-D70 and TR43P telemeters were 57 ± 2 Hz, 40 ± 6 Hz, 32 ± 2 Hz and 173 ± 3 Hz, respectively. 5. Simulation of the devices’ dynamic performance by applying their frequency responses to a high-fidelity recording of arterial pressure demonstrated that the devices have sufficient bandwidth to accurately record arterial waveform dynamics. Experiments were also performed to determine how routine laboratory use and maintenance of the catheter affects the frequency response of the telemeters. Provided no air bubbles were introduced, these showed that the telemeters’ frequency responses were robust to the maintenance procedures of tip removal and gel application. 6. The frequency response measurements, combined with simulation results, demonstrate that the systems tested have adequate dynamic performance to record arterial pressure. en
dc.format.medium 8 en
dc.relation.ispartofseries Clinical and Experimental Pharmacology and Physiology en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0305-1870/ en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.subject arterial pressure pulse pressure telemetry en
dc.title Frequency response of implantable blood pressure telemetry systems en
dc.type Journal Article en
dc.identifier.doi 10.1111/j.1440-1681.2010.05406.x en
pubs.issue 8 en
pubs.begin-page 862 en
pubs.volume 37 en
dc.rights.holder Copyright: 2010 The Authors. Journal compilation; Blackwell Publishing Asia Pty Ltd. en
dc.identifier.pmid 20497422 en
pubs.author-url http://onlinelibrary.wiley.com/doi/10.1111/j.1440-1681.2010.05406.x/abstract en
pubs.end-page 869 en
dc.rights.accessrights http://purl.org/eprint/accessRights/RestrictedAccess en
pubs.subtype Article en
pubs.elements-id 119995 en
pubs.org-id Bioengineering Institute en
pubs.org-id ABI Associates en
pubs.org-id Engineering en
pubs.org-id Department of Electrical, Computer and Software Engineering en
pubs.org-id Engineering Science en
pubs.org-id Medical and Health Sciences en
pubs.org-id Medical Sciences en
pubs.org-id Physiology Division en
pubs.org-id Science en
pubs.org-id Science Research en
pubs.org-id Maurice Wilkins Centre (2010-2014) en
dc.identifier.eissn 1440-1681 en
pubs.record-created-at-source-date 2011-11-03 en
pubs.dimensions-id 20497422 en


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