MRI phase contrast velocity and flow errors in turbulent stenotic jets

ResearchSpace/Manakin Repository

Show simple item record O'Brien, Kieran en Cowan, Brett en Jain, Manali en Stewart, Ralph en Kerr, Andrew en Young, Alistair en 2011-09-06T02:10:09Z en 2008 en
dc.identifier.citation J Magn Reson Imaging 28(1):210-218 Jul 2008 en
dc.identifier.issn 1053-1807 en
dc.identifier.uri en
dc.description.abstract Purpose To clarify the use of MRI phase contrast (PC), as an alternative to Doppler echocardiography, when measuring high-velocity turbulent jets associated with stenotic valvular disease. Materials and Methods In vivo PC aortic stroke volume (SV) was compared with ventricular SV in 31 patients with moderate to severe aortic stenosis (AS). Two in vitro pipe experiments were conducted to evaluate errors in steady stenotic and nonstenotic turbulent flows. Results The average in vivo error in SV was −24% in the left-ventricular (LV) outflow tract (LVOT) and −41% in the aortic root. Errors were most prominent in patients with the highest Doppler peak velocities. In vitro nonstenotic flow experiments showed accurate flow measurement with an average error of 1.8%. Significant errors were found in the in vitro stenotic flow, which reduced with shorter echo times (TE): average error −166/−67/−25/−13/−8.8% for TEs of 4.8/4.0/3.3/2.2/2.0 msec. In both the in vivo and in vitro stenotic experiments the errors were associated with signal loss in the flow-compensated magnitude image. Conclusion Signal loss is associated with flow errors in stenotic jets. Current clinically available PC pulse sequences with TE >2 msec may not accurately quantify flow for severe lesions. en
dc.language EN en
dc.publisher Wiley-Liss, Inc. en
dc.relation.ispartofseries JMRI-Journal of Magnetic Resonance Imaging en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from en
dc.rights.uri en
dc.subject aortic stenosis en
dc.subject phase contrast en
dc.subject turbulence en
dc.subject jet en
dc.subject errors en
dc.subject BLOOD-FLOW en
dc.subject QUANTIFICATION en
dc.subject AREA en
dc.subject INTENSITY en
dc.subject ACCURACY en
dc.subject DISTRIBUTIONS en
dc.subject APPEARANCE en
dc.title MRI phase contrast velocity and flow errors in turbulent stenotic jets en
dc.type Journal Article en
dc.identifier.doi 10.1002/jmri.21395 en
pubs.issue 1 en
pubs.begin-page 210 en
pubs.volume 28 en
dc.rights.holder Copyright: 2008 Wiley-Liss, Inc. en
dc.identifier.pmid 18581344 en
pubs.end-page 218 en
dc.rights.accessrights en
pubs.subtype Article en
pubs.elements-id 80238 en Bioengineering Institute en ABI Associates en Medical and Health Sciences en Medical Sciences en Anatomy and Medical Imaging en School of Medicine en Medicine Department en
pubs.record-created-at-source-date 2010-09-01 en
pubs.dimensions-id 18581344 en

Full text options

Full text for this item is not available in ResearchSpace.

Find Full text

This item appears in the following Collection(s)

Show simple item record


Search ResearchSpace

Advanced Search