A Flexible Approach to 6,5-Benzannulated Spiroketals

Wilson, Zoe; Hubert, JG; Brimble, Margaret

dc.contributor.author	Wilson, Zoe	en
dc.contributor.author	Hubert, JG	en
dc.contributor.author	Brimble, Margaret	en
dc.date.accessioned	2011-09-18T21:45:47Z	en
dc.date.issued	2011-07	en
dc.identifier.citation	EUR J ORG CHEM 2011(20-21):3938-3945 Jul 2011	en
dc.identifier.issn	1434-193X	en
dc.identifier.uri	http://hdl.handle.net/2292/7983	en
dc.description.abstract	A novel route to simple 6,5-benzannulated spiroketal analogues has been developed. A convergent Horner–Wadsworth–Emmons olefination enabled ready assembly of the spiroketal precursors. Use of a benzyl protecting group strategy enabled an efficient one-pot hydrogenation/deprotection/spiroketalisation process to be employed providing a robust method to access a range of substituted aromatic monobenzannulated spiroketals.	en
dc.language	EN	en
dc.publisher	WILEY-BLACKWELL	en
dc.relation.ispartofseries	EUR J ORG CHEM	en
dc.rights	Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/1434-193X/	en
dc.rights.uri	https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm	en
dc.subject	Spiroketals	en
dc.subject	Olefination	en
dc.subject	Hydrogenation	en
dc.subject	Cyclisation	en
dc.subject	Synthetic methods	en
dc.subject	PRODUCT-LIKE SCAFFOLDS	en
dc.subject	BIOLOGICAL-ACTIVITY	en
dc.subject	CHEMICAL VARIATION	en
dc.subject	CONVERGENT ROUTE	en
dc.subject	RUBROMYCINS	en
dc.subject	PURPUROMYCIN	en
dc.subject	DERIVATIVES	en
dc.subject	DESIGN	en
dc.title	A Flexible Approach to 6,5-Benzannulated Spiroketals	en
dc.type	Journal Article	en
dc.identifier.doi	10.1002/ejoc.201100345	en
pubs.issue	20-21	en
pubs.begin-page	3938	en
pubs.volume	2011	en
dc.rights.holder	Copyright: 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim	en
pubs.end-page	3945	en
dc.rights.accessrights	http://purl.org/eprint/accessRights/RestrictedAccess	en
pubs.subtype	Article	en
pubs.elements-id	217506	en
pubs.org-id	Science	en
pubs.org-id	Chemistry	en
pubs.org-id	Science Research	en
pubs.org-id	Maurice Wilkins Centre (2010-2014)	en
pubs.record-created-at-source-date	2011-10-21	en