Synthesis of the FG ring fragment of pectenotoxins 1-9

Heapy, Amanda; Brimble, Margaret

dc.contributor.author	Heapy, Amanda	en
dc.contributor.author	Brimble, Margaret	en
dc.date.accessioned	2011-09-18T22:35:12Z	en
dc.date.issued	2010	en
dc.identifier.citation	TETRAHEDRON 66(29):5424-5431 17 Jul 2010	en
dc.identifier.issn	0040-4020	en
dc.identifier.uri	http://hdl.handle.net/2292/7987	en
dc.description.abstract	The synthesis of the FG ring fragment common to pectenotoxins 1-9 is reported. The successful, convergent synthesis relied on high yielding routes to access two key intermediates; aldehyde 1 and phosphonium salt 2. A Z-selective Wittig reaction gave access to advanced linear precursor 3, which was converted to FG ring fragment 4 using two sequential cyclization reactions. (C) 2010 Elsevier Ltd. All rights reserved.	en
dc.language	EN	en
dc.publisher	PERGAMON-ELSEVIER SCIENCE LTD	en
dc.relation.ispartofseries	TETRAHEDRON	en
dc.rights	Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0040-4020/	en
dc.rights.uri	https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm	en
dc.subject	Pectenotoxins	en
dc.subject	Shellfish toxins	en
dc.subject	Wittig reaction	en
dc.subject	Sharpless asymmetric dihydroxylation	en
dc.subject	Horner/Wadsworth/Emmons reaction	en
dc.subject	STEREOCONTROLLED CYCLIZATION	en
dc.subject	ALKOXIDE PRECOORDINATION	en
dc.subject	ASYMMETRIC SYNTHESES	en
dc.subject	AB SPIROACETAL	en
dc.subject	PART II	en
dc.subject	COMMON	en
dc.subject	HYDROGENATION	en
dc.subject	PRECURSOR	en
dc.subject	SUBUNIT	en
dc.subject	ACCESS	en
dc.title	Synthesis of the FG ring fragment of pectenotoxins 1-9	en
dc.type	Journal Article	en
dc.identifier.doi	10.1016/j.tet.2010.05.027	en
pubs.issue	29	en
pubs.begin-page	5424	en
pubs.volume	66	en
dc.rights.holder	Copyright: 2010 Elsevier Ltd	en
pubs.end-page	5431	en
dc.rights.accessrights	http://purl.org/eprint/accessRights/RestrictedAccess	en
pubs.subtype	Article	en
pubs.elements-id	119856	en
pubs.org-id	Science	en
pubs.org-id	Chemistry	en
pubs.org-id	Science Research	en
pubs.org-id	Maurice Wilkins Centre (2010-2014)	en
pubs.record-created-at-source-date	2011-06-30	en