3-[5-(tert-butyldimethylsilyloxy)-3-(3,5-dinitrobenzoyl)-1-oxo-2-(phenylmethoxy)hexyl]-4-(phenylmethyl)-2-oxazolidinone

Abstract

A mixture of alcohol 1 (104 mg, 0.20 mmol) [1], triethylamine (41 l, 0.30 mmol) and 3,5-dinitrobenzoyl chloride (55 mg, 0.24 mmol) in dichloromethane (2 ml) was stirred for 2 h. at 30ºC. The reaction mixture was poured into saturated aqueous sodium hydrogen carbonate (5 ml), extracted into ethyl acetate (2 x 10 ml), washed with water (2 x 5 ml) and dried over sodium sulfate. ...