dc.contributor.author |
Brimble, Margaret |
en |
dc.contributor.author |
Robinson, James |
en |
dc.contributor.author |
Merten, Joern |
en |
dc.contributor.author |
Beuzenberg, V |
en |
dc.contributor.author |
Dragunow, Michael |
en |
dc.contributor.author |
Holland, P |
en |
dc.contributor.author |
Mountfort, D |
en |
dc.date.accessioned |
2011-09-18T22:49:01Z |
en |
dc.date.issued |
2006 |
en |
dc.identifier.citation |
Synlett 2006(10):1610-1612 2006 |
en |
dc.identifier.issn |
0936-5214 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/8014 |
en |
dc.description.abstract |
Treatment of the shellfish toxin gymnodimine with one equivalent of molecular bromine at -78 °C resulted in stereoselective formation of a novel ring-expansion product. Participation of the spiromine unit in this novel bromine-induced ring expansion reaction provides insight into how the reactivity of spiroimine moiety may contribute to the toxicity of this marine biotoxin when activated by the presence of an appropriate environmental electrophile. |
en |
dc.language |
EN |
en |
dc.publisher |
Georg Thieme Verlag Stuttgart New York |
en |
dc.relation.ispartofseries |
Synlett |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0936-5214/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.subject |
gymnodimine |
en |
dc.subject |
shellfish toxin |
en |
dc.subject |
ring expansion |
en |
dc.subject |
1,2,3,5,6,7-HEXAHYDROPYRROLIZINIUM PERCHLORATES |
en |
dc.subject |
PIPERIDINES |
en |
dc.subject |
ROUTE |
en |
dc.title |
A Novel Bromine-Induced Ring Expansion of the Spiroimine Moiety of the Shellfish Toxin Gymnodimine |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1055/s-2006-941605 |
en |
pubs.issue |
10 |
en |
pubs.begin-page |
1610 |
en |
pubs.volume |
2006 |
en |
dc.rights.holder |
Copyright: Georg Thieme Verlag Stuttgart New York |
en |
pubs.end-page |
1612 |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
69533 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
Medical Sciences |
en |
pubs.org-id |
Pharmacology |
en |
pubs.org-id |
Science |
en |
pubs.org-id |
Chemistry |
en |
pubs.org-id |
Science Research |
en |
pubs.org-id |
Maurice Wilkins Centre (2010-2014) |
en |
pubs.record-created-at-source-date |
2010-09-01 |
en |