Synthesis of Fish Antifreeze Neoglycopeptides Using Microwave-assisted "Click Chemistry"

Show simple item record Miller, Nicole en Williams, Geoffrey en Brimble, Margaret en 2011-09-19T00:05:00Z en 2009 en
dc.identifier.citation Organic Letters 11(11):2409-2412 2009 en
dc.identifier.issn 1523-7060 en
dc.identifier.uri en
dc.description.abstract Microwave-enhanced click glycoconjugation of a propargylated α-GalNAc sugar moiety with an azido-functionalized amino acid or multiazido-functionalized peptides using a catalytic quantity of Cu(I) enabled a high-yielding and rapid synthesis of a “Tn-antigen mimic” and click analogues of antifreeze glycopeptides, thus demonstrating a valuable synthetic platform for the synthesis of biologically relevant neoglycopeptides. en
dc.language EN en
dc.publisher American Chemical Society en
dc.relation.ispartofseries Organic Letters en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from en
dc.rights.uri en
dc.subject PROTEINS en
dc.subject GLYCOPROTEINS en
dc.subject CYCLOADDITION en
dc.subject ANALOGS en
dc.subject ICE en
dc.title Synthesis of Fish Antifreeze Neoglycopeptides Using Microwave-assisted "Click Chemistry" en
dc.type Journal Article en
dc.identifier.doi 10.1021/ol9005536 en
pubs.issue 11 en
pubs.begin-page 2409 en
pubs.volume 11 en
dc.rights.holder Copyright: 2009 American Chemical Society en
dc.identifier.pmid 19473046 en
pubs.end-page 2412 en
dc.rights.accessrights en
pubs.subtype Article en
pubs.elements-id 86201 en Science en Chemistry en Science Research en Maurice Wilkins Centre (2010-2014) en
pubs.record-created-at-source-date 2010-09-01 en
pubs.dimensions-id 19473046 en

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