An Enantioselective Formal Synthesis of Berkelic Acid.

McLeod, MC; Wilson, ZE; Brimble, MA

dc.contributor.author	McLeod, MC	en
dc.contributor.author	Wilson, ZE	en
dc.contributor.author	Brimble, MA	en
dc.date.accessioned	2011-09-19T01:33:49Z	en
dc.date.available	2011-09-19T01:33:49Z	en
dc.date.issued	2011	en
dc.identifier.citation	Org Lett 14 Sep 2011	en
dc.identifier.issn	1523-7060	en
dc.identifier.uri	http://hdl.handle.net/2292/8056	en
dc.description.abstract	An enantioselective formal synthesis of berkelic acid is described. The key step involves a late-stage silyl enol ether addition to a benzannulated oxonium ion with subsequent spiroketalization leading to construction of the tetracyclic core. Thermodynamically controlled equilibration under acidic conditions affords the desired spiroketal configuration as a single diastereoisomer.	en
dc.language	ENG	en
dc.relation.ispartof	Organic Letters	en
dc.rights	Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/1523-7060/	en
dc.rights.uri	https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm	en
dc.source.uri	http://dx.doi.org/10.1021/ol202265g	en
dc.title	An Enantioselective Formal Synthesis of Berkelic Acid.	en
dc.type	Journal Article	en
dc.identifier.doi	10.1021/ol202265g	en
dc.rights.holder	Copyright: 2011 American Chemical Society	en
dc.rights.accessrights	http://purl.org/eprint/accessRights/RestrictedAccess	en
pubs.subtype	Article	en
pubs.elements-id	225025	en
pubs.org-id	Faculty of Science	en
pubs.org-id	Chemistry	en