dc.contributor.author |
Brimble, Margaret |
en |
dc.contributor.author |
Gorsuch, Stephen |
en |
dc.date.accessioned |
2011-09-19T01:55:45Z |
en |
dc.date.issued |
1999 |
en |
dc.identifier.citation |
Australian Journal of Chemistry 52 (10), 965-969, 1999 |
en |
dc.identifier.issn |
0004-9425 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/8084 |
en |
dc.description.abstract |
The deprotonation of 2-methyl-4,5,6,7-tetrahydro-3H-azepine (5) using lithium diisopropylamide was effected at −30°C in tetrahydrofuran. Addition of deuterium oxide resulted in >95% incorporation of deuterium at the exocyclic position. Addition of a range of electrophiles to the organolithium species afforded moderate yields of the alkylation products wherein substitution at the exocyclic position had occurred. |
en |
dc.language |
EN |
en |
dc.relation.ispartofseries |
Australian Journal of Chemistry |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0004-9425/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.subject |
ALKALOID SYNTHESIS |
en |
dc.subject |
SHELLFISH |
en |
dc.subject |
REAGENTS |
en |
dc.title |
Deprotonation and alkylation of 2-methyl-4,5,6,7-tetrahydro-3H-azepine |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1071/CH99094 |
en |
pubs.issue |
10 |
en |
pubs.begin-page |
965 |
en |
pubs.volume |
52 |
en |
dc.rights.holder |
Copyright: 1999 CSIRO |
en |
pubs.end-page |
969 |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
2022 |
en |
pubs.org-id |
Science |
en |
pubs.org-id |
Chemistry |
en |
pubs.org-id |
Science Research |
en |
pubs.org-id |
Maurice Wilkins Centre (2010-2014) |
en |
pubs.record-created-at-source-date |
2010-09-01 |
en |