Abstract:
The asymmetric dihydroxylation of unsaturated spiroacetals 1, 2, 3 was effected using the cinchona alkaloid ligands (DHQ)2-PHAL. (DHQD)2-PHAL and DHQ-IND, DHQD-IND with OSO4, K3Fe(CN)6 and methanesulfonamide. Kinetic resolution of the spiroacetals was achieved and the reactions were monitored by chiral gas chromatography.