Synthesis of the bis-spiroacetal C-25-C-40 moiety of the antimitotic agent spirastrellolide B using a bis-dithiane deprotection/spiroacetalisation sequence

Chen, JLY; Brimble, Margaret

dc.contributor.author	Chen, JLY	en
dc.contributor.author	Brimble, Margaret	en
dc.date.accessioned	2011-09-21T22:30:40Z	en
dc.date.issued	2010	en
dc.identifier.citation	Chem Commun (Camb) 46(22):3967-3969 14 Jun 2010	en
dc.identifier.issn	1359-7345	en
dc.identifier.uri	http://hdl.handle.net/2292/8213	en
dc.description.abstract	Use of a bis-dithiane deprotection-tandem bis-spiroacetalisation sequence was key to the successful synthesis of the [5,6,6]-bis-spiroacetal of the antimitotic agent spirastrellolide B, achieved in a highly convergent fashion involving successive dithiane alkylations.	en
dc.language	EN	en
dc.publisher	ROYAL SOC CHEMISTRY	en
dc.relation.ispartofseries	CHEM COMMUN	en
dc.rights	Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/1359-7345/	en
dc.rights.uri	https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm	en
dc.subject	ANION RELAY CHEMISTRY	en
dc.subject	ESTER-PART 1	en
dc.subject	METHYL-ESTER	en
dc.subject	ASYMMETRIC DIHYDROXYLATION	en
dc.subject	STRATEGIC CONSIDERATIONS	en
dc.subject	A CONSTRUCTION	en
dc.subject	SUBUNIT	en
dc.subject	FRAGMENT	en
dc.subject	TRIOXADISPIROKETAL	en
dc.subject	DERIVATIVES	en
dc.title	Synthesis of the bis-spiroacetal C-25-C-40 moiety of the antimitotic agent spirastrellolide B using a bis-dithiane deprotection/spiroacetalisation sequence	en
dc.type	Journal Article	en
dc.identifier.doi	10.1039/c0cc00056f	en
pubs.issue	22	en
pubs.begin-page	3967	en
pubs.volume	46	en
dc.rights.holder	Copyright: 2010 The Royal Society of Chemistry	en
dc.identifier.pmid	20445924	en
pubs.end-page	3969	en
dc.rights.accessrights	http://purl.org/eprint/accessRights/RestrictedAccess	en
pubs.subtype	Article	en
pubs.elements-id	119518	en
pubs.org-id	Science	en
pubs.org-id	Chemistry	en
pubs.org-id	Science Research	en
pubs.org-id	Maurice Wilkins Centre (2010-2014)	en
pubs.record-created-at-source-date	2011-06-30	en
pubs.dimensions-id	20445924	en