dc.contributor.author |
Brimble, Margaret |
en |
dc.contributor.author |
Bryant, Christina |
en |
dc.date.accessioned |
2011-09-21T22:52:31Z |
en |
dc.date.issued |
2006 |
en |
dc.identifier.citation |
Chemical Communications 2006(43):4506-4508 2006 |
en |
dc.identifier.issn |
1359-7345 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/8230 |
en |
dc.description.abstract |
The first synthesis of the spiroacetal-containing anti-Helicobacter pylori agents ent-CJ-12,954 and ent-CJ-13,014 is reported based on the union of a heterocycle-activated spiroacetal-containing sulfone fragment with a phthalide-containing aldehyde fragment; comparison of the 1H and 13C NMR data, optical rotations and HPLC retention times of the synthetic compounds (3S,2″S,5″S,7″S)-(1a) and (3S,2″S,5″R,7″S)-(2a) and the (3R)-diastereomers (3R,2″S,5″S,7″S)-(1b) and (3R,2″S,5″R,7″S)-(2b) with the naturally occurring compounds established that the synthetic isomers (1a) and (2a) were in fact enantiomeric to the natural products CJ-12,954 and CJ-13,014. |
en |
dc.language |
EN |
en |
dc.publisher |
ROYAL SOC CHEMISTRY |
en |
dc.relation.ispartofseries |
Chemical Communications |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/1359-7345/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.subject |
(+)-SPIROLAXINE METHYL-ETHER |
en |
dc.subject |
ULCER DISEASE |
en |
dc.subject |
SPOROTRICALE |
en |
dc.subject |
CONDENSATION |
en |
dc.subject |
MANAGEMENT |
en |
dc.subject |
ACID |
en |
dc.title |
Synthesis of the Spiroacetal-Containing Anti-Helicobacter Pylori Agents CJ-12,954 and CJ-13,014 |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1039/b612757f |
en |
pubs.issue |
43 |
en |
pubs.begin-page |
4506 |
en |
pubs.volume |
2006 |
en |
dc.rights.holder |
Copyright: 2006 The Royal Society of Chemistry |
en |
dc.identifier.pmid |
17283800 |
en |
pubs.end-page |
4508 |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
69526 |
en |
pubs.org-id |
Science |
en |
pubs.org-id |
Chemistry |
en |
pubs.org-id |
Science Research |
en |
pubs.org-id |
Maurice Wilkins Centre (2010-2014) |
en |
pubs.record-created-at-source-date |
2010-09-01 |
en |
pubs.dimensions-id |
17283800 |
en |