dc.contributor.author |
Leal, RMF |
en |
dc.contributor.author |
Callow, S |
en |
dc.contributor.author |
Callow, P |
en |
dc.contributor.author |
Blakeley, MP |
en |
dc.contributor.author |
Cardin, CJ |
en |
dc.contributor.author |
Denny, William |
en |
dc.contributor.author |
Teixeira, SCM |
en |
dc.contributor.author |
Mitchell, EP |
en |
dc.contributor.author |
Forsyth, VT |
en |
dc.date.accessioned |
2011-11-17T17:16:00Z |
en |
dc.date.issued |
2010-11 |
en |
dc.identifier.citation |
Acta Crystallographica Section D: Biological Crystallography 66(11):1244-1248 Nov 2010 |
en |
dc.identifier.issn |
0907-4449 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/9216 |
en |
dc.description.abstract |
Recent developments in instrumentation and facilities for sample preparation have resulted in sharply increased interest in the application of neutron diffraction. Of particular interest are combined approaches in which neutron methods are used in parallel with X-ray techniques. Two distinct examples are given. The first is a single-crystal study of an A-DNA structure formed by the oligonucleotide d(AGGGGCCCCT)2, showing evidence of unusual base protonation that is not visible by X-ray crystallography. The second is a solution scattering study of the interaction of a bisacridine derivative with the human telomeric sequence d(AGGGTTAGGGTTAGGGTTAGGG) and illustrates the differing effects of NaCl and KCl on this interaction. |
en |
dc.language |
EN |
en |
dc.publisher |
international union of crystallography |
en |
dc.relation.ispartofseries |
Acta Crystallographica Section D: Biological Crystallography |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0907-4449/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.subject |
neutron diffraction |
en |
dc.subject |
X-ray diffraction |
en |
dc.subject |
nucleic acids |
en |
dc.subject |
DNA |
en |
dc.subject |
acridine derivatives |
en |
dc.subject |
deuteration |
en |
dc.subject |
SAXS |
en |
dc.subject |
SANS |
en |
dc.subject |
III ANTIFREEZE PROTEIN |
en |
dc.subject |
FIBER DIFFRACTION |
en |
dc.subject |
A-DNA |
en |
dc.subject |
CRYSTALLOGRAPHIC ANALYSIS |
en |
dc.subject |
DOUBLE HELIX |
en |
dc.subject |
RESOLUTION |
en |
dc.subject |
HYDRATION |
en |
dc.subject |
PROGRAM |
en |
dc.subject |
CRYSTALLIZATION |
en |
dc.title |
Combined neutron and X-ray diffraction studies of DNA in crystals and solutions |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1107/S0907444910017713 |
en |
pubs.issue |
11 |
en |
pubs.begin-page |
1244 |
en |
pubs.volume |
66 |
en |
dc.rights.holder |
Copyright: International Union of Crystallography |
en |
dc.identifier.pmid |
21041945 |
en |
pubs.end-page |
1248 |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
178190 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
Medical Sciences |
en |
pubs.org-id |
Auckland Cancer Research |
en |
pubs.org-id |
Science |
en |
pubs.org-id |
Science Research |
en |
pubs.org-id |
Maurice Wilkins Centre (2010-2014) |
en |
pubs.record-created-at-source-date |
2011-11-17 |
en |
pubs.dimensions-id |
21041945 |
en |