Advanced glycation end products and its receptor (RAGE) are increased in patients with COPD

Advanced glycation end products and its receptor (RAGE) are increased in patients with COPD

(Corresponding Author) Wu, L ; Ma, L ; Nicholson, Louise ; Black, PN
Identifier: http://hdl.handle.net/2292/9224
Issue Date: 2011-03
Reference: Respiratory Medicine 105(3):329-336 Mar 2011
Rights: Copyright: Elsevier Ltd.
Rights (URI): https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm

Abstract:

Advanced Glycation End products (AGEs) are the products of nonenzymatic glycation and oxidation of proteins and lipids. Formation of AGEs is increased in response to hyperglycaemia, reactive oxygen species and ageing. AGEs are proinflammatory and can modify the extracellular matrix. RAGE (Receptor for Advanced Glycation End Products) mediates some of the effects of AGEs.

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DOI: 10.1016/j.rmed.2010.11.001
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