Abstract:
Adrien Albert is one of the greatest medicinal chemists of the mid-20th century whose role in the development of acridine-based antimalarial and anti-bacterial drugs during World War II is a marked event in the history of drug development. A brief survey of the work in the Auckland Cancer Society Research Centre (ACSRC) on acridines and related compounds as DNA-binding cancer drugs illustrates the common conclusions drawn from Adrien Albert's achievements.