Population-based case-control studies

Abstract

We discuss methods for the analysis of case­control studies in which the controls are drawn using a complex sample survey. The most straightforward method is the standard survey approach based on weighted versions of population estimating equations. We also look at more efficient methods and compare their robustness to model mis­specification in simple cases. Case­control family studies, where the within­cluster structure is of interest in its own right, are also discussed briefly.