ResearchSpace@Auckland
University of Auckland Research Repository - ResearchSpace
ResearchSpace is an online archive for the University of Auckland and contains full text theses and other research outputs.
University Staff: Update your Discovery Profiles and deposit full text content using Te Waka Huia Rangahau | Research Outputs.
Communities in ResearchSpace
Select a community to browse its collections.
Recent Submissions
National Recommendations for Spinal Muscular Atrophy Newborn Screening in Australia and Aotearoa New Zealand
(2024-10-05) Kariyawasam, Didu; Farrar, Michelle; Meagher, Christian; Heather, Natasha; Bhattacharya, Kaustav; Sampaio, Hugo; Cini, Julie; Lau, Chiyan; Mas, Emilie; Burrows, Linda; Greenslade, Mark; Heller, Raoul; Allcock, Richard; Divanisova, Sandra; Carrivick, Simon; Kay, Alexandra; Siu, Carol; Webster, Dianne; Ranieri, Enzo; Moore, Francesca; Crisp, Gabrielle; Pitt, James; Greed, Lawrence; de Hora, Mark
This Guideline has been developed to provide a child and family focused approach to newborn screening (NBS) for spinal muscular atrophy (SMA). It is intended to span the entire healthcare journey, from screening through to diagnosis and immediate post-diagnosis assessment and care for the newborn and their family.
21-Deoxycortisone: A Novel Newborn Screening Marker of Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency
(2019-08-03) De Hora, Mark; Heather, N; Webster, D; Albert, B; Hofman, Paul
• Measurement of 21DE in dried bloodspots can be used as an additional marker for CAH in the newborn periods. The test appears to sufficiently accurate and precise for routine use.
• Use of 21DE as an additional appears to improve the sensitivity of screening if appropriate thresholds for first tier screening are established.
• Longer prospective studies that use both 21DF and 21DE in second-tier protocols are warranted
• Development of a first-tier screening test for 21DE by immunoassay has the potential for further Improvements to Screening
Better Together: Multi-Generational Living in Auckland
(ResearchSpace@Auckland, 2025) Fullerton, Bri; Stout, Julie
Auckland lacks the diversity of affordable housing options to allow extended families to live together. Whether it be for social or cultural needs or for economic reasons, household compositions are changing, and this requires strategic housing design. Auckland’s current focus on prioritising medium density housing fails to accommodate larger households and families as they evolve. The gap in the market for medium density housing that facilitates multi-generational living necessitates flexible and adaptable floor plans, the inclusion of outdoor spaces, wheelchair accessibility, and thresholds that support privacy and social connections.
Through design-led research and research-led design, a blend of collages and drawings help to examine both multi-generational living and medium density housing. Considering New Zealand’s context of escalating living costs and a growing and ageing population, the research responds to the question: How can the design of medium density housing facilitate multi-generational living and optimise social connectivity?
The author draws from the literature on multi-generational living and medium density housing, proposing a hypothetical project in Hobsonville Point that caters to changing household needs while enhancing nature and neighbourhood connectivity. This thesis critiques the existing regulations for the project’s selected two-thirds of a hectare site, offering a conceptual design of twenty-four terraced houses to inspire future development.
The Fundamentals of Care in Practice: A Qualitative Contextual Inquiry
(Wiley, 2025-04) Pene, Bobbie-Jo; Aspinall, Cathleen; Komene, Ebony; Slark, Julia; Gott, Merryn; Robinson, Jackie; Parr, Jenny M
Empirical evidence on the Fundamentals of Care framework and its relevance to practice is increasing. However, there is a need to understand the evidence in practice and determine how best to evaluate caring activities. This exploratory study aimed to understand current nursing practice with the Fundamentals of Care framework, how nurses understand the framework, and what is essential to patients receiving care. The objectives were (1) to observe nurses in practice and record nurse-patient interactions against the Fundamentals of Care framework dimensions, (2) to probe the nurse's understanding of the framework, (3) to explore what is important to patients when receiving care from nurses, (4) to explore the nurse's and patient's understanding of culture and spirituality, and (5) to identify the barriers and facilitators to delivering integrated care. The study identified four key findings: (1) nurse-patient interactions centred around completing tasks and the physical aspects of care, (2) there are crucial gaps in nurses' ability to connect with their patients and establish a good nurse-patient relationship, (3) integrated fundamental care was not evident in the behaviours and narratives of the nurses, and (4) the context in which care is delivered significantly impacts how nurses work particularly the challenges of using technology and electronic records. Healthcare organisations and nursing leaders need to consider the implications of nurses prioritising the organisation's efficiency-driven requirements over establishing a therapeutic relationship and integrating the patient's care needs. More work is required to support nurses in delivering integrated fundamental care.
Selective Nonoperative Management of Abdominal Stab Wounds in Low‐ and Middle‐Income Countries: A Systematic Review and Meta‐Analysis
(Wiley, 2025-03-17) Moffatt, Samuel; Biggs, Daniel; Kong, Victor; Clarke, Damian
ABSTRACTBackgroundSelective nonoperative management (SNOM) of abdominal stab wounds is a well‐established approach to managing these injuries and has been practiced since the 1960s. This systematic review and meta‐analysis provides an up‐to‐date analysis of the safety and feasibility of this management strategy in upper‐middle‐income, lower‐middle‐income, low‐income, and least developed countries and describes evidence of how this management has evolved.MethodsMedline (via PubMed), Google Scholar, Scopus, Embase, the International Clinical Trials Registry, and Web of Science were searched for studies describing SNOM of abdominal stab wounds in patients ≥ 16 years old in upper‐middle‐income, lower‐middle‐income, low‐income, and least developed countries. Study characteristics and method of SNOM (use of computed tomography scanning vs. serial examination only) were extracted. Pooled results for failure of SNOM, mortality, complications, and length of stay (LOS) were analyzed.ResultsTwenty studies were selected containing 1505 patients initially managed nonoperatively with 245 ultimately requiring surgical intervention. The pooled risk of failure of SNOM was 0.14 (95% CI = 0.08–0.22). There was zero reported mortality in patients selected for SNOM. LOS was generally higher in patients undergoing primary operative management, and complications were also reported as being more frequent in primary operative management patients.ConclusionSNOM of abdominal stab wounds is a safe method of managing these injuries. Computed tomography is now commonly used to aid in decision‐making about suitability for attempted SNOM in lower‐resource settings.