Wáng, Yì Xiáng JDiacinti, DanieleAparisi Gómez, Maria PilarSantiago, Fernando RuizBecce, FabioTagliafico, Alberto StefanoPrakash, MaheshIsaac, AmandaDalili, DanoobGriffith, James FGuglielmi, GiuseppeBazzocchi, Alberto2024-12-022024-12-022024-12(2024). Skeletal Radiology, 53(12), 2563-2574.0364-2348https://hdl.handle.net/2292/70842When a low-energy trauma induces an acute vertebral fracture (VF) with clinical symptoms, a definitive diagnosis of osteoporotic vertebral fracture (OVF) can be made. Beyond that, a "gold" radiographic standard to distinguish osteoporotic from non-osteoporotic VFs does not exist. Fracture-shaped vertebral deformity (FSVD) is defined as a deformity radiographically indistinguishable from vertebral fracture according to the best of the reading radiologist's knowledge. FSVD is not uncommon among young populations with normal bone strength. FSVD among an older population is called osteoporotic-like vertebral fracture (OLVF) when the FSVD is likely to be associated with compromised bone strength. In more severe grade deformities or when a vertebra is collapsed, OVF diagnosis can be made with a relatively high degree of certainty by experienced readers. In "milder" cases, OVF is often diagnosed based on a high probability rather than an absolute diagnosis. After excluding known mimickers, singular vertebral wedging in older women is statistically most likely an OLVF. For older women, three non-adjacent minimal grade OLVF (< 20% height loss), one minimal grade OLVF and one mild OLVF (20-25% height loss), or one OLVF with ≥ 25% height loss, meet the diagnosis of osteoporosis. For older men, a single OLVF with < 40% height loss may be insufficient to suggest the subject is osteoporotic. Common OLVF differential diagnoses include X-ray projection artifacts and scoliosis, acquired and developmental short vertebrae, osteoarthritic wedging, oncological deformities, deformity due to high-energy trauma VF, lateral hyperosteogeny of a vertebral body, Cupid's bow, and expansive endplate, among others.Print-ElectronicItems in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher.https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htmhttp://creativecommons.org/licenses/by/4.0/HumansSpinal FracturesDiagnosis, DifferentialRadiographyPrevalenceConsensusFemaleOsteoporotic FracturesOsteoporosisRadiographVertebral deformityVertebral fracture32 Biomedical and Clinical Sciences3202 Clinical SciencesPhysical Injury - Accidents and Adverse EffectsWomen's HealthAging4.1 Discovery and preclinical testing of markers and technologiesMusculoskeletal1103 Clinical SciencesJournal Article10.1007/s00256-024-04678-42024-11-27Copyright: The authors38662094 (pubmed)http://purl.org/eprint/accessRights/OpenAccess1432-216110.1007/s00256-024-04678-4