The Power of Genomics

Abstract

The promise of genomics-guided precision oncology is highlighted by recent approvals of molecularly guided therapies coupled with companion diagnostic tests. A critical limitation of genomics-guided oncology is that it is unlikely to serve Indigenous cancer patients unless Indigenous rights-based approaches to genomics-guided cancer research and clinical care are prioritized. Relevant Indigenous datasets that can support precision oncology are needed. Indigenous access to and governance over key infrastructure are needed. We must grow and empower an Indigenous workforce with subject matter expertise and clinical acumen to ensure that genomics-guided precision oncology can sustainably benefit Indigenous cancer patients